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Document 0062
DOCN M9630062
TI [Update on microsporidiosis in humans]
DT 9603
AU Atias A; Departamento de Parasitologia, Facultad de Medicina,
Universidad; de Chile, Santiago de Chile.
SO Rev Med Chil. 1995 Jun;123(6):762-72. Unique Identifier : AIDSLINE
MED/96041702
AB The importance of microsporidium as an opportunistic agent in
immunocompromised and AIDS patients is reviewed. Five strains of the
agent have been described: Encephalitozoon, Enterocytozoon, Nosema,
Pleistophora and Septata. The clinical presentation may be as 1)
Generalized infections with multisystemic involvement, specially of the
central nervous system; 2) Intestinal, that is the most important and
frequent localization in man, and that may cause death in AIDS patients;
3) Ocular, that affects cornea, conjunctiva and may extend to paranasal
sinuses; 4) Liver and biliary tract infection with granulomatous
lesions, hepatic necrosis or sclerosing colangitis and 5) Muscular,
affecting skeletal muscle. The diagnosis is difficult and is established
finding spores in the affected tissues with light or electron
microscopy. Lately, the diagnosis of intestinal microsporidiosis is made
looking for faecal spores. The resistant wall of spores hampers
treatment. However, good results are obtained with Albendazole in
intestinal microsporidiosis.
DE Animal *AIDS-Related Opportunistic Infections/DIAGNOSIS/DRUG THERAPY/
IMMUNOLOGY Child Child, Preschool English Abstract Female Human
Infant *Intestinal Diseases, Parasitic/DIAGNOSIS/DRUG
THERAPY/IMMUNOLOGY Male *Microspora Infections/DIAGNOSIS/DRUG
THERAPY/IMMUNOLOGY
*Microsporida/CLASSIFICATION/PHYSIOLOGY/PATHOGENICITY JOURNAL ARTICLE
REVIEW REVIEW, TUTORIAL
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).